AQA A-Level Biology: Epigenetic Control of Gene Expression (8.2.2) Lesson

This fully-resourced lesson is designed for teachers delivering the second part of point 8.2.2 of the AQA A-Level Biology specification. It covers how epigenetics, through DNA methylation and histone acetylation, regulates gene expression.

Key Features:

• Comprehensive Coverage: Explains how methylation inhibits transcription and how decreased acetylation condenses chromatin, preventing gene expression.
• Interactive Activities: Includes challenges, discussions, and a fill-in-the-blank task to reinforce learning.
• Real-World Applications: Examines a study on DNA methylation and atherosclerosis with cross-topic questions (topics 1–7).
• Teacher-Focused Design: Provides structured content for clear, engaging delivery.

This resource ensures teachers can confidently explain epigenetics while aligning with the AQA specification.

• Exam Board: AQA
• Subject: Biology
• Level: A-Level
• Resource Type: Lesson
• Year: 2025
• Year Group/s: Year 12 and Year 13

This resource was created by GJHeducation