AQA A-Level Biology: Transcription Factors (8.2.2) Lesson

This fully-resourced and engaging lesson is designed for teachers delivering the first part of point 8.2.2 of the AQA A-Level Biology specification. It explains how the transcription of target genes can be stimulated or inhibited by transcription factors, while reinforcing connections to protein synthesis from Topic 4.2.

Key Features:

• Detailed Content Coverage: Explains the role of transcription factors, including DNA-binding and ligand-binding domains, and their interaction with promoter regions to initiate transcription.
• Clear Connections to Curriculum: Links to prior learning on genome, proteome, and protein synthesis to strengthen understanding and encourage discussion.
• Engaging Real-World Examples: Introduces DELLA proteins and their role in inhibiting plant development, along with oestrogen’s mechanism of action, to illustrate transcription regulation.
• Interactive and Challenging Tasks: Includes a sequence-ordering activity where students follow the steps of oestrogen binding to its transcription factor, solidifying their comprehension of key processes.
• Teacher-Centered Design: Offers a structured and adaptable approach for delivering this complex topic in an engaging and accessible manner.

This resource provides biology teachers with the tools to effectively deliver lessons on transcription factors and gene regulation, ensuring clarity and student engagement while meeting AQA A-Level Biology specification requirements.

• Exam Board: AQA
• Subject: Biology
• Level: A-Level
• Resource Type: Lesson
• Year: 2025
• Year Group/s: Year 12 and Year 13

This resource was created by GJHeducation